Host: RuPaul.  Featured guests: Miss Richfield 1981, Harvey Fierstein, Billie Jean King, Susan Sarandon.

Summary: The episode begins with a segment that explores the push to broaden American views of gender identity. The Real to Reel segment is about the documentary, Venus of Mars. The next segment is a profile of the Midwestern drag performer, Miss Richfield. Another segment examines tensions between the intersex community and medical professionals. Harvey Fierstein's Out Takes segment is titled "We Are What We Are." Billie Jean King, RuPaul and Susan Sarandon provide PSAs during the episode.

Note: Some audio content removed due to copyright restrictions.
32:38 - 33:31: The B-52's, "The World's Green Laughter"
54:10 - 55:43: Boy George, "She Was Never He"

Host: Laura Linney.  Featured guests: RuPaul, Sonja Sohn, Barry Monush, Michelangelo Signorile, David Collins, Will Wikle, Stuart Krasnow, Joan Garry, Harvey Fierstein, Beth Anthony, Chip Arndt, Rosie O'Donnell, Mathew St. Patrick.

Summary: This episode is a rebroadcast of episode 1404, originally broadcast January 2005. The episode focuses primarily on LGBT representation on television and in advertising. The episode begins with a segment that explores the evolution of queer imagery throughout TV history. The next segment examines how the gay identity is constructed in advertising, followed by a look at reality television as it relates to LGBTQ representation. The next segment goes behind-the-scenes of The L Word. Harvey Fierstein's Out Takes segment is titled "Where's Your Anger?" Beth Anthony, Chip Arndt, Rosie O'Donnell and Mathew St. Patrick provide PSAs during the episode.

Note: Some audio content removed due to copyright restrictions.
54:19 - 55:48: Pet Shop Boys, "Positive Role Model"

Host: Kate Clinton. Guests: John Scagliotti, Charles Ignacio, Katherine Linton, Anita Lo, Barbara Rick, Jerry Herman, Carol Channing, Angela Lansbury.

Summary: The first episode of season 14 begins with a trip through In the Life's early years, followed by a profile of celebrity chef Anita Lo. The Real to Reel segment spotlights Barbara Rick's documentary, In Good Conscience, about a Catholic nun countering the church's view of homosexuality. Jerry Herman is profiled in a rebroadcast of a segment originally from episode 1109. The Coming Out Stories segment features six individuals sharing their personal memories of coming out to their loved ones.

Host: Sharon Gless.  Featured guests: Howard Grossman, Ron Valdiserri, Larry Kramer.

Summary: This episode is a rebroadcast of episode 1412, which originally broadcast September 2005. It begins with a segment examining how perceptions of AIDS have changed over time, the seriousness of the crisis and new HIV treatments. The next segment is about methamphetamine use in the LGBT community, particularly relating to the increased risk of contracting HIV. Another segment spotlights homeless LGBT youth in Los Angeles and New York City, highlighting their struggles and HIV risk. The Real to Reel segment is about Of Men and Gods, a Haitian documentary that explores the nature of homosexual orientation within the context of voodoo and the shadow of AIDS.