Host: Wilson Cruz.  Featured guests: Wendi O'Neal, Jordan Roth, Scott Heim, Samantha Gellar, Holly Hughes, Regie Cabico, Alix Olson, Emanuel Xavier, Madonna.

Summary: This episode is a reversion featuring segments from previous episodes as well as new segments. Excerpts are taken from previously aired episodes 701, 805, 902, 904 and 905, and cover such topics as teen suicide, LGBT youth support organizations, slam poetry, and art censorship. The In the Arts segment covers queer Latino and Latina writers, as well as Emily Solomon's play, The Last Time I Wore a Dress. Youth activist Wendi O'Neal of Atlanta's Spelman College is profiled. The Out Artists Speak Out segment features Jordan Roth and Scott Heim, and the In the News segment covers the Gay, Lesbian and Straight Education Network (GLSEN) conference in Chicago. The episode also spotlights the film, That's a Family.

Host: Staceyann Chin.  Featured guests: Howard Dean, Harvey Fierstein, Judy Shepard, Judith Light.

Summary: The episode begins with a historical look at circuit parties and the controversies surrounding them. Next, lesbian rabbis face issues surrounding their sexuality and faith. The next segment focuses on Host Homes in Minnesota, where gay homeless youth are taken in by gay couples. Next is a profile of Howard Dean. The Real to Reel segment is about Dangerous Living, a documentary on homosexuals living in third world countries. Then, older gay men discuss aging and living with AIDS. Harvey Fierstein's Out Takes segment is titled "Being Useful." Judy Shepard gives a PSA on about the Matthew Shepard Foundation, and Judith Light provides the celebrity ID.

Host: Staceyann Chin.  Featured guests: George Ratliff, Emil Wilbekin, Harvey Fierstein, Maple Flagg, Judy Shepard, Bill Thomas, Jade Estrada.

Summary: This episode is a reversion featuring segments from previous episodes as well as new segments. Excerpts from episodes 1109, 1209, 1301, 1305 and 1306 explore LGBT harassment in high school, religion in the classroom, George Ratliff's Hell House, the Host Home organization in Minnesota, VIBE Magazine, and a push for a gay youth center in Newark, New Jersey. Harvey Fierstein's Out Takes segment is titled "Freedom Of and From." The Lisa/Gill Foundation, Maple Flagg, Judy Shepard, Bill Thomas and Jade Estrada provide PSAs during the episode.

Host: Ani DiFranco. Guests: Emily Frerichs, Jeremy Hooper, Miss Elizabeth Latex.

Summary: The episode begins with a segment about Emily Frerichs, an openly gay 17-year-old Christian in a small Iowa community. The next segment spotlights blogger Jeremy Hooper. Another segment profiles Miss Elizabeth Latex, a transgendered youth on a journey through New York City's ballroom community. The Coming Out Stories segment features three LGBT youths sharing their experiences of coming out.

Host: Emil Wilbekin.  Featured guests: E.J. Graff, Evan Wolfson, Eric Criswell, Martin Bedogne, Harvey Fierstein, Gavin Newsom, Jason Stuart, Judith Light.

Summary: This episode is a rebroadcast of episode 1312, which originally broadcast September 2004. The final episode of season 12 begins with a marriage montage segment highlighting then-recent events surrounding same-sex marriage. The next segment presents the history of the institution of marriage, followed by conservative Christians providing their viewpoints on gay marriage. Another segment spotlights a New York City same-sex couple whose wedding plans were waylaid by a major illness. The next segment examines the current state of transgender marriage in the United States, with a profile of a transgender couple. The Real to Reel segment is about Out in the Cold, a documentary film on homeless gay youth. Another segment considers the recognition of Canadian same sex marriages in the United States. Harvey Fierstein's Out Takes segment is titled "First Amendment. Gavin Newsom, Jason Stuart, Judith Light and Log Cabin Republicans provide historical PSAs during the episode.

Note: Some audio content removed due to copyright restrictions.
55:59 - 57:32: Lesley Gore, "Wedding Bell Blues"

Host: Sharon Gless.  Featured guests: Howard Grossman, Ron Valdiserri, Larry Kramer.

Summary: This episode is a rebroadcast of episode 1412, which originally broadcast September 2005. It begins with a segment examining how perceptions of AIDS have changed over time, the seriousness of the crisis and new HIV treatments. The next segment is about methamphetamine use in the LGBT community, particularly relating to the increased risk of contracting HIV. Another segment spotlights homeless LGBT youth in Los Angeles and New York City, highlighting their struggles and HIV risk. The Real to Reel segment is about Of Men and Gods, a Haitian documentary that explores the nature of homosexual orientation within the context of voodoo and the shadow of AIDS.

Featured guests:  George Chauncey, David Paterson.

Summary:  The episode begins with a segment about the ballroom scene in Newark, New Jersey. The A conversation with… segment features Professor George Chauncey and New York State Governor David Paterson discussing their shared battle against bigotry and discrimination, and the current fight for marriage equality. The Real to Reel segment is about On the Downlow, a documentary about gay men in the black community.

Featured guest: Sirdeaner Walker.

Summary: The episode begins with a segment about high depression and suicide rates among bullied LGBT youth, featuring Sirdeaner Walker among the family members fighting for federal legislation to protect their children. The In the States segment focuses on Ohio, considers such topics as domestic partner benefits and employee discrimination, and spotlights locals with deep ties to the LGBT community organizing for equal rights in the state.

Featured guest: Carson Kressley.

Summary: The episode begins with a segment featuring LGBT youth sharing stories about correctional institutions, along with advocates fighting for change. The next segment investigates how enforcing the concepts of gender-appropriate dress and behavior affects the lives of LGBT youth.